COLUMBUS, Miss. – A review paper by Dr. Jiben Roy, professor of chemistry at Mississippi University for Women, is aimed at providing information to improve safety in the manufacture of medicines. It was published in The Journal of Excipients and Food Chemicals sponsored by the International Pharmaceutical Excipients Council-America.

Excipients are chemicals other than active medicinal chemicals. The paper, titled Development of Cracks on Delayed Release Film of Hygroscopic Cores: A Review of the Tablet and Coating Formulations, Coating Process and Storage Conditions, Vol. 6, NO 3, is intended for individuals in the pharmaceutical industry and provides useful information on what to do and what not to do while making film coating for medicinal tablets.

Dr. Roy explained that pharmaceutical industries make tablets and also film coated tablets for delayed release and sustained release tablets for the benefit of patients.

In the process of making these tablets, he said, a number of problems may occur, including cracking of the film. The goal of Roy’s review paper is to assist people in that industry in ways to avoid cracking films of tablets in storage.

Dr. Roy said there are multiple research papers available on this particular issue but they are not assessed and presented in one paper. The matter is more thoroughly discussed in Roy’s review article, along with suggested remedies.

In addition, Dr. Roy and his co-author, Manjurul Kader, worked together to gather the information from surveying scientific literature.

“My co- worker, who has worked with me in the past, is currently working in the pharmaceutical industry. This is how we identified the issue and looked for research papers that have already been published and summarized those, including our experiences into the paper, Roy said.

The International Pharmaceutical Excipients Council promotes quality and best practices in making tablets or any pharmaceutical dosage forms that individuals have to mix with many excipients.

Roy’s review paper is published in the Journal of Excipients and Food Chemicals, and the paper can find be found at

Dr. Roy is working on another project which includes his students from The W.

The project focuses on heat stability of curcumin in turmeric spice which is beneficial to humans as an anti-inflammatory agent, according to Roy. The curcumin of turmeric is also found to be useful for Alzheimer’s and cancer, he said. The research paper has been submitted for publication.

Dr. Roy is an organic chemist and a pharmaceutical scientist. In 2011, he published a textbook on pharmaceutical sciences.

He earned his doctorate in organic chemistry from the University of Saskatchewan (Canada) in 1983 and went on to complete his doctoral fellowship at the Hawaii Natural Energy Institute, University of Hawaii at Manoa from 1984 to 1985.

Roy joined The W in 2004, where he teaches organic chemistry, general chemistry, introductory chemistry, pharmaceutical sciences and environmental sciences.

Oct. 30, 2015
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